DURAN® Autoclave Push-on Cap

The DURAN® Autoclave Bottle and Push-on Cap System provides a convenient and secure solution for steam sterilization of liquid media, eliminating the need for pre- or post-autoclaving adjustments. Available in three sizes, the DURAN® Autoclave Bottle is paired with a self-venting, push-on cap, ensuring safe and efficient sterilization. Manufactured from DURAN® borosilicate 3.3 glass, these bottles offer exceptional thermal shock resistance, making them a trusted choice. Steam sterilization is one of the most reliable and widely adopted methods for ensuring liquid sterility. Typically performed in an autoclave, the process works by exposing the material directly to steam at the required temperature and pressure for a defined period. When autoclaving liquids in glass bottles, it is essential that screw closures are only loosely applied. If bottles are sealed tightly, pressure can build up, potentially leading to breakage or even explosive failure. Safe autoclaving of sealed bottles is only possible if the autoclave is equipped with support pressure compensation. Alternatives to screw closures include vented caps and ported caps that can accommodate small sterile-venting filters. While effective, such closures may pose challenges for validation in GLP processes and should be carefully evaluated before use.